Evan Peters was born in St. Louis, Missouri to Phillip and Julie Peters. He got into acting when his family moved to Grand Blanc, Michigan. Peters wanted to meet the Olsen twins and decided the best way to do that was to become an actor. He enrolled in a local talent agency where Bob Lamb saw him and put him on tape for his now-deceased manager, Craig Wargo. Craig told Peters to move out to Los Angeles and audition. With the support of both his parents, Peters moved out to Burbank. Taking it one year at a time, Peters would audition and continue to land promising rolls in MGM's Sleepover, Disney's Phil of the Future and a starring role on the ABC series The Days. Peters also landed a role in the ensemble cast of ABC's sci-fi thriller series, Invasion.

Supporting roles in films such as Gardens of the Night, An American Crime and Never Back Down, and guest starring roles on The Mentalist, House, Monk and The Office have showcased Peters’ comedic diversity and dramatic depth. In 2010, Peters played a supporting role in the comic book feature motion picture, Kick-Ass. Peters maintains that the best way to stay in this business is "to have a good work ethic, aesthetic sensibility, and a good sense of humor... Russell Crowe said that and he's awesome. Throws phones and stuff.."